HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: Q9H4D1 (Q9H4D1)
Protein kinase
Gene: dik

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26972000
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 784
+	Hs
		883504 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		972586 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		883489 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		1053188 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		685027 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		883512 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		923838 FKB1A_HUMAN (151-247): 2.87e-21: 90.3: 26.73		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		684571 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		883470 FKB1A_HUMAN (151-247): 2.87e-21: 90.3: 26.73		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		1034933 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		ANKK1_HUMAN (333-607): 8.82e-45: 174: 22.10
+	Hs
		1035071 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		972616 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		556701 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		ANK1_HUMAN (341-754): 2.07e-113: 381: 30.29
+	Hs
		684893 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		ANKK1_HUMAN (333-607): 8.82e-45: 174: 22.10
+	Hs
		685142 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74