HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 463
+	Hs
		1035059 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Hs
		1053256 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		685116 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Hs
		1053257 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Hs
		685119 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RUVB1_HUMAN (8-451): 0: 655: 42.67