HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: NUDC (Q9Y266)
Nuclear migration protein nudC (Nuclear distribution protein C homolog)
Gene: NUDC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 331
+	Hs
		1034922 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		NUDC3_HUMAN (8-331): 1.43e-97: 294: 27.67
+	Hs
		972546 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		NUDC3_HUMAN (8-331): 1.43e-97: 294: 27.67
+	Hs
		1034946 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		NUDC2_HUMAN (173-331): 5e-32: 118: 21.74
+	Hs
		1053258 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		NUDC_HUMAN (1-331): 6.28e-136: 390: 100.00
+	Hs
		685120 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		NUDC_HUMAN (1-331): 6.28e-136: 390: 100.00
+	Hs
		1053060 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		NUDC3_HUMAN (8-331): 1.43e-97: 294: 27.67
+	Hs
		1284716 FKB10_HUMAN (134-285): 5.25e-13: 72.9: 20.51		NUDC1_HUMAN (143-263): 1.25e-27: 115: 26.45