HitPredict

Interactor 1: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31871319
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Rho_Binding
Common GO terms GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0031267 - small GTPase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024