HitPredict

Interactor 1: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1354 Hs			1 783
+	Hs
		254493 ROCK2_HUMAN (7-1344): 0: 714: 64.97		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		148970 CTRO_HUMAN (13-1292): 1.39e-130: 447: 20.62		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1071653 KS6A2_HUMAN (74-340): 4.56e-88: 304: 28.62		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		850672 KS6A3_HUMAN (6-381): 3.43e-86: 299: 23.64		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1073440 KS6A1_HUMAN (74-338): 1.23e-85: 297: 29.56		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172335 ST38L_HUMAN (57-373): 1.24e-80: 275: 43.18		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1069619 STK38_HUMAN (57-373): 6.26e-78: 267: 42.90		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1137875 MRCKA_HUMAN (668-1327): 3.6e-64: 242: 12.45		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172454 MRCKB_HUMAN (806-1251): 1.11e-22: 108: 12.31		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		149045 CTRO_HUMAN (13-1292): 1.39e-130: 447: 20.62		CMYA5_HUMAN (262-606): 5.31e-36: 149: 19.32
+	Hs
		1069648 STK38_HUMAN (57-373): 6.26e-78: 267: 42.90		TRIM6_HUMAN (195-774): 1.16e-86: 284: 12.69
+	Hs
		149258 CTRO_HUMAN (13-1292): 1.39e-130: 447: 20.62		TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70
+	Hs
		1049033 STK38_HUMAN (57-373): 6.26e-78: 267: 42.90		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		1071675 KS6A2_HUMAN (74-340): 4.56e-88: 304: 28.62		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Hs
		850697 KS6A3_HUMAN (6-381): 3.43e-86: 299: 23.64		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Mm
		1143596 ST38L_MOUSE (57-373): 1.03e-80: 275: 42.90		TRI27_MOUSE (105-456): 7.29e-11: 67.4: 14.77
+	Hs
		537140 ST38L_HUMAN (57-373): 1.24e-80: 275: 43.18		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		1052661 STK38_HUMAN (57-373): 6.26e-78: 267: 42.90		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		537089 LATS2_HUMAN (48-374): 4.7e-70: 258: 38.77		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77