HitPredict

Interactor 1: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Interactor 2: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 694 Hs			1 1216
+	Hs
		616917 GAB1_HUMAN (1-694): 0: 547: 100.00		PTPRB_HUMAN (912-1214): 2.71e-123: 422: 47.91
+	Hs
		1020092 GAB1_HUMAN (1-694): 0: 547: 100.00		PTPRJ_HUMAN (911-1214): 8.14e-117: 396: 44.48
+	Hs
		577020 GAB1_HUMAN (1-694): 0: 547: 100.00		PTPRA_HUMAN (922-1196): 1.24e-99: 337: 35.48
+	Hs
		441197 GAB1_HUMAN (1-694): 0: 547: 100.00		PTPRC_HUMAN (918-1204): 1.51e-71: 264: 28.26
+	Hs
		617108 GAB1_HUMAN (1-694): 0: 547: 100.00		PTPRG_HUMAN (937-1200): 8.02e-53: 205: 29.09