HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043066 - negative regulation of apoptotic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 1821
+	Hs
		1016273 BIRC3_HUMAN (1-604): 0: 676: 100.00		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		903199 BIRC3_HUMAN (1-604): 0: 676: 100.00		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1036051 BIRC3_HUMAN (1-604): 0: 676: 100.00		TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71
+	Hs
		1035967 BIRC3_HUMAN (1-604): 0: 676: 100.00		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		1035858 BIRC3_HUMAN (1-604): 0: 676: 100.00		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		197014 BIRC3_HUMAN (1-604): 0: 676: 100.00		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		254080 BIRC3_HUMAN (1-604): 0: 676: 100.00		WDR1_HUMAN (433-682): 6.63e-16: 85.3: 12.22
+	Hs
		254081 BIRC2_HUMAN (2-604): 0: 643: 72.31		WDR1_HUMAN (433-682): 6.63e-16: 85.3: 12.22
+	Hs
		152869 XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21		APAF_HUMAN (305-887): 1.12e-58: 225: 11.63