HitPredict

Interactor 1: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Interactor 2: ITF2 (Q60722)
Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: Tcf4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

The method score is based on:

Property	Details
Experiments	15578569, 31125668, 16007074, 12874278, 21103407
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0010629 - negative regulation of gene expression and 3 others more... GO:0016525 - negative regulation of angiogenesis GO:0030154 - cell differentiation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	781
Mm

1	670

Service provided by Combinatics, Japan

Last updated: 11Aug2025