HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 783
+	Hs
		1035866 BIRC3_HUMAN (1-604): 0: 676: 100.00		DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41
+	Hs
		1036017 BIRC3_HUMAN (1-604): 0: 676: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1035944 BIRC3_HUMAN (1-604): 0: 676: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134021 BIRC3_HUMAN (1-604): 0: 676: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571436 BIRC3_HUMAN (1-604): 0: 676: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757598 BIRC3_HUMAN (1-604): 0: 676: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		181728 BIRC7_HUMAN (13-165): 1.87e-34: 134: 21.80		DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48
+	Hs
		181725 RNF34_HUMAN (547-604): 6.54e-19: 90.8: 36.21		DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48