HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007283 - spermatogenesis GO:0042981 - regulation of apoptotic process and 1 others more... GO:0051726 - regulation of cell cycle
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 456
+	Hs
		1036213 BIRC3_HUMAN (1-604): 0: 676: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Dm
		1097141 DIAP2_DROME (9-100): 4.66e-25: 110: 31.52		RUVB1_DROME (1-455): 0: 660: 79.56
+	Dm
		1097116 DIAP2_DROME (9-100): 4.66e-25: 110: 31.52		RUVB2_DROME (5-455): 0: 640: 45.25