HitPredict

Interactor 1: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Interactor 2: UB2Q2 (Q8WVN8)
Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2)
Gene: UBE2Q2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21113135
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 618 Hs			1 375
+	Hs
		1035925 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		UB2Q2_HUMAN (1-375): 0: 624: 100.00
+	Hs
		962884 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UB2Q2_HUMAN (1-375): 0: 624: 100.00
+	Hs
		957741 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UB2Q2_HUMAN (1-375): 0: 624: 100.00
+	Hs
		962844 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UB2Q1_HUMAN (6-375): 0: 598: 72.47