HitPredict

Interactor 1: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Interactor 2: UBP15 (Q9Y4E8)
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)
Gene: USP15

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23524849
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 618 Hs			1 981
+	Hs
		301386 BIRC2_HUMAN (1-618): 0: 702: 100.00		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		1206095 MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Hs
		1036241 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Hs
		963037 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Mm
		1141990 XIAP_MOUSE (20-173): 1.62e-31: 130: 28.66		UBP15_MOUSE (1-981): 0: 858: 97.66
+	Hs
		849996 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UBP11_HUMAN (9-946): 0: 661: 43.58
+	Hs
		301385 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		301374 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		177638 BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		1174178 RFFL_HUMAN (567-618): 2.51e-17: 85.8: 42.31		UBP43_HUMAN (213-938): 5.85e-122: 400: 24.10
+	Hs
		962954 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP26_HUMAN (290-957): 3.12e-71: 256: 16.55
+	Hs
		271073 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		271165 BIRC7_HUMAN (299-618): 4.32e-34: 133: 20.94		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		777082 BIRC6_HUMAN (34-167): 3.57e-31: 132: 19.42		UBP8_HUMAN (602-930): 8.61e-59: 221: 25.68
+	Hs
		957762 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UBP47_HUMAN (624-977): 2.99e-56: 214: 14.94
+	Hs
		271156 MYLIP_HUMAN (558-617): 3.91e-22: 101: 41.67		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		177733 BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12		UBP22_HUMAN (772-933): 1.82e-57: 208: 32.20
+	Hs
		962832 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP51_HUMAN (287-469): 1.56e-14: 80.1: 33.33