Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1
Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.98 | 1.00 | 0.994 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25311206, 25416956, 25723488, 25686248, 26075355, 26187466, 26413874, 26902585, 26942676, 28359760, 29976090, 30120248, 30581152, 16169070, 32296183, 31375263, 31434890, 31857589, 33393215, 33545068 and 14 others
more... |
Identification Methods | affinity chromatography technology, two hybrid, x-ray crystallography, pull down, fluorescent resonance energy transfer, biochemical, protein complementation assay, proximity labelling technology, isothermal titration calorimetry, nuclear magnetic resonance and 5 others
more... |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PB1~PB1, UBA_5~UBA_5, ZZ~ZZ |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000407 - phagophore assembly site GO:0000422 - autophagy of mitochondrion GO:0000423 - mitophagy GO:0000425 - pexophagy and 71 others more... |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024