HitPredict

Interactor 1: G5E8T2 (G5E8T2)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: Ttc3

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1979 Mm			1 1161
+	Mm
		291321 TTC3_MOUSE (1-1979): 0: 2305: 99.85		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		551641 TTC3_HUMAN (1-1979): 0: 2182: 75.91		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		858688 PPP5_HUMAN (211-401): 3.74e-42: 164: 22.92		MRCKB_HUMAN (421-862): 5.66e-16: 85.6: 11.45
+	Dm
		1176818 Q9VH81_DROME (231-348): 2.53e-32: 135: 33.90		Q7JQV2_DROME (691-960): 1.41e-17: 90.7: 16.72
+	Dm
		1366917 Q9VH81_DROME (231-348): 2.53e-32: 135: 33.90		Q9VY43_DROME (617-985): 1.21e-14: 81.5: 12.27
+	Hs
		148359 DESP_HUMAN (1337-1700): 8.63e-13: 76.5: 10.99		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		551596 DESP_HUMAN (1337-1700): 8.63e-13: 76.5: 10.99		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		1137901 DNJC7_HUMAN (123-395): 4.71e-10: 66.5: 14.49		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		684450 STIP1_HUMAN (221-518): 1e-23: 109: 16.19		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Ce
		183698 STIP1_CAEEL (229-394): 7.69e-20: 94.9: 20.46		MYO4_CAEEL (684-971): 4.54e-09: 63.2: 17.97
+	Mm
		93570 DESP_MOUSE (1363-1724): 1.9e-11: 71.9: 12.17		MYH9_MOUSE (773-1161): 3.4e-11: 70.2: 11.72
+	Mm
		93578 DESP_MOUSE (1363-1724): 1.9e-11: 71.9: 12.17		PLEC_MOUSE (557-1006): 2.01e-09: 64.5: 13.40