Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 30581152, 32123815, 34079125, 33545068, 34037656, 34774801, 21935636, 12813044, 20808283, 16861740, 24879152, 29343546, 33226137, 34488032, 15802564, 25007327, 19250911, 20562859
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, ZZ~ZZ
Common GO terms GO:0000407 - phagophore assembly site
GO:0005654 - nucleoplasm
GO:0005770 - late endosome
GO:0005776 - autophagosome
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 440
Hs

1 966
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024