HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: AINX (Q16352)
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)
Gene: INA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030154 - cell differentiation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 499
+	Hs
		422388 SQSTM_HUMAN (1-440): 0: 760: 100.00		NFM_HUMAN (9-480): 1.71e-96: 313: 47.43
+	Hs
		443497 SQSTM_HUMAN (1-440): 0: 760: 100.00		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Mm
		589635 SQSTM_MOUSE (1-440): 0: 731: 90.72		VIME_MOUSE (73-418): 4.06e-97: 303: 55.20
+	Hs
		1036707 SQSTM_HUMAN (1-440): 0: 760: 100.00		K2C73_HUMAN (7-410): 3.68e-78: 255: 31.88
+	Hs
		319691 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		K2C6B_HUMAN (59-410): 7.35e-59: 205: 30.23
+	Hs
		319759 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		K2C6C_HUMAN (59-410): 7.2e-59: 205: 30.51