HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22565157
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044877 - protein-containing complex binding GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 451
+	Hs
		1036855 SQSTM_HUMAN (1-440): 0: 760: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		933194 SQSTM_HUMAN (1-440): 0: 760: 100.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428185 SQSTM_HUMAN (1-440): 0: 760: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		933789 SQSTM_HUMAN (1-440): 0: 760: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		1175004 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		319990 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		319791 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		428212 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		TBB5_HUMAN (1-439): 0: 695: 40.77