HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: NOD2 (Q9HC29)
Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1)
Gene: NOD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

The method score is based on:

Property	Details
Experiments	30833792, 35066577, 36221902, 23437331
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001659 - temperature homeostasis GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0019899 - enzyme binding and 5 others more... GO:0019901 - protein kinase binding GO:0035556 - intracellular signal transduction GO:0043130 - ubiquitin binding GO:0044877 - protein-containing complex binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	440
Hs

1	1040

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024