HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: CACO1 (Q9P1Z2)
Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3)
Gene: CALCOCO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33545068
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 691
+	Hs
		1036703 SQSTM_HUMAN (1-440): 0: 760: 100.00		TAXB1_HUMAN (15-680): 1.63e-57: 210: 24.60
+	Mm
		1112813 SQSTM_MOUSE (1-440): 0: 731: 90.72		TAXB1_MOUSE (15-680): 2.28e-49: 187: 23.21
+	Hs
		1025370 SQSTM_HUMAN (1-440): 0: 760: 100.00		CACO2_HUMAN (260-475): 1.2e-10: 66: 16.67
+	Hs
		1201837 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		TAXB1_HUMAN (15-680): 1.63e-57: 210: 24.60
+	Hs
		1078859 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		ITSN1_HUMAN (123-648): 6.73e-30: 129: 13.21
+	Hs
		1056153 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		CACO1_HUMAN (1-691): 6.91e-62: 221: 100.00
+	Hs
		1056069 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		TAXB1_HUMAN (15-680): 1.63e-57: 210: 24.60
+	Mm
		1118137 HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50		MYH10_MOUSE (53-572): 2.35e-25: 114: 10.42
+	Hs
		1025382 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		CACO2_HUMAN (260-475): 1.2e-10: 66: 16.67