Interactor 1: MED21 (Q13503)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7) (hSrb7)
Gene: MED21
Interactor 2: MED4 (Q9NPJ6)
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)
Gene: MED4
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.955 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25281560, 24981860, 35271311, 28514442, 33961781, 24882805 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Med21~Med4 |
| Common GO terms | GO:0003712 - transcription coregulator activity GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 5 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
