HitPredict

Interactor 1: G5E9A7 (G5E9A7)
DM1 locus, WD repeat containing (Dystrophia myotonica-containing WD repeat motif, isoform CRA_a)
Gene: DMWD

Interactor 2: PPARA (Q07869)
Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)
Gene: PPARA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 649 Hs			1 468
+	Hs
		103714 G5E9A7_HUMAN (16-649): 9.26e-130: 398: 100.00		RXRG_HUMAN (2-465): 8.06e-118: 354: 22.72
+	Hs
		103731 G5E9A7_HUMAN (16-649): 9.26e-130: 398: 100.00		NR1H3_HUMAN (6-464): 2.51e-109: 332: 23.70
+	Hs
		93994 G5E9A7_HUMAN (16-649): 9.26e-130: 398: 100.00		F1D8P7_HUMAN (19-464): 3.7e-109: 332: 22.44
+	Hs
		370061 WDR20_HUMAN (9-635): 1.07e-118: 367: 53.17		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		103739 G5E9A7_HUMAN (16-649): 9.26e-130: 398: 100.00		NR1D2_HUMAN (284-442): 3.74e-25: 110: 37.50
+	Hs
		370394 SKI8_HUMAN (175-444): 1.4e-46: 168: 16.08		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		245556 TBL1X_HUMAN (321-639): 5.94e-36: 144: 13.06		THB_HUMAN (99-466): 3.59e-114: 345: 27.42
+	Hs
		245573 TBL1X_HUMAN (321-639): 5.94e-36: 144: 13.06		PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36
+	Hs
		1269559 SKI8_HUMAN (175-444): 1.4e-46: 168: 16.08		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Hs
		245574 TBL1X_HUMAN (321-639): 5.94e-36: 144: 13.06		HNF4A_HUMAN (77-464): 1.45e-103: 318: 22.11
+	Hs
		196938 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		369362 RACK1_HUMAN (155-448): 1.06e-25: 110: 17.73		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		500505 TBL1R_HUMAN (363-648): 7.4e-19: 92.1: 10.00		THB_HUMAN (99-466): 3.59e-114: 345: 27.42
+	Hs
		740596 TBL1R_HUMAN (363-648): 7.4e-19: 92.1: 10.00		PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36
+	Hs
		370377 TBL1R_HUMAN (363-648): 7.4e-19: 92.1: 10.00		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		197064 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Hs
		929598 RACK1_HUMAN (155-448): 1.06e-25: 110: 17.73		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Hs
		488022 TBL1R_HUMAN (363-648): 7.4e-19: 92.1: 10.00		RARA_HUMAN (19-466): 9.06e-103: 316: 26.49
+	Hs
		1269746 NLE1_HUMAN (83-241): 2.52e-19: 93.3: 11.95		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Xl
		546250 TB1RA_XENLA (363-648): 3.99e-19: 92.9: 10.00		THAA_XENLA (42-466): 4.32e-99: 305: 22.20