HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: EMAL4 (Q9HC35)
Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120)
Gene: EML4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0000278 - mitotic cell cycle GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton and 1 others more... GO:0072686 - mitotic spindle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 450 Hs			1 981
+	Hs
		428448 TBB5_HUMAN (1-429): 0: 704: 93.94		EMAL4_HUMAN (1-981): 0: 652: 100.00
+	Hs
		1313678 TBB2B_HUMAN (1-430): 0: 703: 93.72		EMAL4_HUMAN (1-981): 0: 652: 100.00
+	Hs
		933982 TBB4B_HUMAN (1-427): 0: 703: 93.91		EMAL4_HUMAN (1-981): 0: 652: 100.00
+	Hs
		201925 TBB4B_HUMAN (1-427): 0: 703: 93.91		WDR62_HUMAN (233-942): 1.85e-81: 291: 16.45
+	Hs
		325564 TBB3_HUMAN (1-450): 0: 723: 100.00		EMAL2_HUMAN (393-952): 5.15e-48: 184: 10.16
+	Hs
		325567 TBB8_HUMAN (1-427): 0: 705: 87.59		EMAL2_HUMAN (393-952): 5.15e-48: 184: 10.16
+	Hs
		325560 TBB4B_HUMAN (1-427): 0: 703: 93.91		EMAL2_HUMAN (393-952): 5.15e-48: 184: 10.16
+	Hs
		325572 TBB2B_HUMAN (1-430): 0: 703: 93.72		EMAL2_HUMAN (393-952): 5.15e-48: 184: 10.16
+	Hs
		127920 TBB3_HUMAN (1-450): 0: 723: 100.00		EMAL1_HUMAN (531-953): 1.99e-32: 137: 7.81
+	Hs
		428163 TBB5_HUMAN (1-429): 0: 704: 93.94		TBL3_HUMAN (194-436): 3.73e-33: 140: 9.80
+	Hs
		127909 TBB5_HUMAN (1-429): 0: 704: 93.94		EMAL1_HUMAN (531-953): 1.99e-32: 137: 7.81
+	Hs
		127928 TBB2B_HUMAN (1-430): 0: 703: 93.72		EMAL1_HUMAN (531-953): 1.99e-32: 137: 7.81
+	Hs
		127921 TBB2A_HUMAN (1-430): 0: 700: 93.49		EMAL1_HUMAN (531-953): 1.99e-32: 137: 7.81
+	Hs
		1037266 TBB3_HUMAN (1-450): 0: 723: 100.00		EMAL6_HUMAN (701-961): 4.38e-18: 92.5: 9.36
+	Hs
		1114109 TBB8_HUMAN (1-427): 0: 705: 87.59		EMAL6_HUMAN (701-961): 4.38e-18: 92.5: 9.36
+	Hs
		1168501 TBB2B_HUMAN (1-430): 0: 703: 93.72		EMAL6_HUMAN (701-961): 4.38e-18: 92.5: 9.36
+	Hs
		267759 TBB3_HUMAN (1-450): 0: 723: 100.00		TAF5L_HUMAN (506-681): 1.92e-11: 69.9: 16.29
+	Hs
		267769 TBB8_HUMAN (1-427): 0: 705: 87.59		TAF5L_HUMAN (506-681): 1.92e-11: 69.9: 16.29
+	Hs
		1104144 TBB2B_HUMAN (1-430): 0: 703: 93.72		EMAL3_HUMAN (740-959): 1.26e-11: 70.9: 10.42
+	Hs
		933831 TBB4B_HUMAN (1-427): 0: 703: 93.91		EMAL3_HUMAN (740-959): 1.26e-11: 70.9: 10.42