HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: KLK11 (Q9UBX7)
Kallikrein-11 (hK11) (EC 3.4.21.-) (Hippostasin) (Serine protease 20) (Trypsin-like protease) [Cleaved into: Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2]
Gene: KLK11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 282
+	Hs
		428722 TBB3_HUMAN (1-450): 0: 723: 100.00		TRY2_HUMAN (30-282): 2.04e-112: 325: 41.50
+	Hs
		1037334 TBB3_HUMAN (1-450): 0: 723: 100.00		KLK6_HUMAN (33-281): 1.24e-104: 305: 42.97
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK1_HUMAN (30-282): 3.58e-106: 310: 39.85
+	Hs
		341273 TBB3_HUMAN (1-450): 0: 723: 100.00		FA9_HUMAN (41-280): 8.63e-94: 286: 33.20
+	Hs
		1037451 TBB3_HUMAN (1-450): 0: 723: 100.00		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		1114231 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK15_HUMAN (44-282): 5.63e-100: 294: 49.00
+	Hs
		1114269 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		428515 TBB5_HUMAN (1-429): 0: 704: 93.94		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		934035 TBB4B_HUMAN (1-427): 0: 703: 93.91		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		1046624 TBB2A_HUMAN (1-430): 0: 700: 93.49		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		1312839 TBB6_HUMAN (1-446): 0: 700: 92.38		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		381331 TBB4A_HUMAN (1-427): 0: 699: 93.21		KLK5_HUMAN (45-282): 7.81e-96: 285: 49.17
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 699: 93.21		PRSS8_HUMAN (34-279): 7.58e-94: 282: 32.12
+	Hs
		836354 TBB3_HUMAN (1-450): 0: 723: 100.00		GRAK_HUMAN (54-279): 1.59e-43: 150: 37.82
+	Hs
		595528 TBB3_HUMAN (1-450): 0: 723: 100.00		GRAH_HUMAN (49-280): 1.07e-39: 140: 38.24
+	Hs
		595536 TBB8_HUMAN (1-427): 0: 705: 87.59		GRAH_HUMAN (49-280): 1.07e-39: 140: 38.24
+	Hs
		428017 TBB5_HUMAN (1-429): 0: 704: 93.94		GRAH_HUMAN (49-280): 1.07e-39: 140: 38.24
+	Hs
		381123 TBB4A_HUMAN (1-427): 0: 699: 93.21		GRAH_HUMAN (49-280): 1.07e-39: 140: 38.24