HitPredict

Interactor 1: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.80	0.648

Property	Details
Experiments	15854902
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~Ras
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2644 Hs			1 184
+	Hs
		787491 MTOR_HUMAN (756-2643): 0: 1254: 15.93		RHEB_HUMAN (1-184): 7.42e-94: 272: 100.00
+	Hs
		787444 MTOR_HUMAN (756-2643): 0: 1254: 15.93		RAB1A_HUMAN (4-183): 1.28e-76: 229: 30.27
+	Hs
		787529 MTOR_HUMAN (756-2643): 0: 1254: 15.93		REBL1_HUMAN (1-184): 1.32e-64: 198: 52.17
+	Hs
		1031531 ATM_HUMAN (772-2644): 0: 1145: 18.85		RHEB_HUMAN (1-184): 7.42e-94: 272: 100.00
+	Sp
		293193 TOR2_SCHPO (756-2643): 0: 1212: 16.46		RHB1_SCHPO (1-184): 6.95e-62: 191: 52.17
+	Sc
		350865 TOR1_YEAST (773-2643): 0: 1173: 16.68		YPT1_YEAST (4-178): 3.04e-73: 221: 28.41
+	Hs
		787446 MTOR_HUMAN (756-2643): 0: 1254: 15.93		RAP1A_HUMAN (5-163): 2.2e-36: 126: 40.85
+	Hs
		486013 MTOR_HUMAN (756-2643): 0: 1254: 15.93		RAP2A_HUMAN (19-183): 6.71e-30: 109: 38.24
+	Hs
		486025 ATM_HUMAN (772-2644): 0: 1145: 18.85		RAP2A_HUMAN (19-183): 6.71e-30: 109: 38.24
+	Hs
		1328163 TRRAP_HUMAN (1161-2644): 0: 857: 13.71		RAB1B_HUMAN (4-173): 8.3e-76: 227: 30.41
+	Hs
		486062 TRRAP_HUMAN (1161-2644): 0: 857: 13.71		RAP2A_HUMAN (19-183): 6.71e-30: 109: 38.24
+	Mm
		918977 PRKDC_MOUSE (1676-2644): 1.08e-138: 491: 16.29		RAB1A_MOUSE (4-183): 1.28e-76: 229: 30.27
+	Mm
		1129551 PK3CB_MOUSE (1993-2612): 1.29e-102: 359: 13.23		DIRA2_MOUSE (1-180): 2.29e-33: 119: 38.25