HitPredict

Interactor 1: ATR (Q13535)
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Gene: ATR

Interactor 2: TELO2 (Q9Y4R8)
Telomere length regulation protein TEL2 homolog (Protein clk-2 homolog) (hCLK2)
Gene: TELO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	17384638, 19097996, 20427287, 20801936, 18160036
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2644 Hs			1 837
+	Mm
		1322171 MTOR_MOUSE (756-2643): 0: 1262: 15.70		TELO2_MOUSE (1-837): 0: 1067: 75.06
+	Hs
		787615 MTOR_HUMAN (756-2643): 0: 1254: 15.93		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Mm
		1143875 ATM_MOUSE (772-2644): 0: 1167: 18.64		TELO2_MOUSE (1-837): 0: 1067: 75.06
+	Hs
		1031650 ATM_HUMAN (772-2644): 0: 1145: 18.85		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Hs
		1377806 TRRAP_HUMAN (1161-2644): 0: 857: 13.71		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Dm
		1213249 TOR_DROME (755-2643): 0: 1224: 16.23		Q8IN05_DROME (121-829): 0: 646: 22.69
+	Sp
		145545 TOR1_SCHPO (761-2643): 0: 1228: 16.33		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sp
		1350677 TOR2_SCHPO (756-2643): 0: 1212: 16.46		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sp
		968997 RAD3_SCHPO (804-2643): 0: 1088: 27.19		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Hs
		944493 PRKDC_HUMAN (1676-2644): 1.8e-143: 506: 16.76		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Hs
		1300095 SMG1_HUMAN (2136-2606): 9.32e-90: 331: 23.20		TELO2_HUMAN (1-837): 0: 1020: 100.00
+	Sp
		1013452 YAMB_SCHPO (789-2644): 0: 832: 12.28		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sc
		744152 ATR_YEAST (781-2643): 0: 969: 21.61		TEL2_YEAST (510-738): 1.01e-63: 228: 20.25
+	Sp
		1336848 TRA1_SCHPO (928-2644): 0: 670: 12.38		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sp
		251731 ATM_SCHPO (1382-2643): 3.84e-176: 608: 18.01		TEL2_SCHPO (332-837): 3.18e-147: 456: 18.82
+	Sc
		744121 ATM_YEAST (1793-2643): 4.24e-110: 397: 21.19		TEL2_YEAST (510-738): 1.01e-63: 228: 20.25