Interactor 1: 4EBP1 (Q13541)
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I)
Gene: EIF4EBP1
Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.768 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12912989, 12747827, 12150926, 16798736, 15767663, 12604610, 33852892, 17502379, 18337751, 18955708, 25940091, 18606717, 16837165, 16824195, 22493283, 21071439, 18722121, 12665511, 24403073, 15066126 and 1 others
more... |
| Identification Methods | affinity chromatography technology, pull down, unspecified method, far western blotting, enzymatic study, anti tag coimmunoprecipitation, in-gel kinase assay |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031929 - TOR signaling |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
