Interactor 1: 4EBP1 (Q13541)
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I)
Gene: EIF4EBP1
Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.55 | 0.512 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20671708 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045947 - negative regulation of translational initiation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
