HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	20850016, 12700765
Identification Methods	unspecified method, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 136
+	Hs
		934735 HDAC1_HUMAN (1-482): 0: 668: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		935063 HDAC2_HUMAN (1-478): 0: 666: 85.92		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952319 HDAC1_HUMAN (1-482): 0: 668: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1086250 HDAC2_HUMAN (1-478): 0: 666: 85.92		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952512 HDAC2_HUMAN (1-478): 0: 666: 85.92		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		111560 HDAC1_HUMAN (1-482): 0: 668: 100.00		K7EK07_HUMAN (1-132): 3.48e-59: 180: 93.18
+	Hs
		828220 HDAC1_HUMAN (1-482): 0: 668: 100.00		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	At
		886469 HDA6_ARATH (5-461): 0: 578: 58.04		H33_ARATH (1-136): 1.13e-61: 187: 93.38
+	Hs
		177255 HDAC3_HUMAN (9-434): 0: 574: 57.94		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Ce
		184839 HDA1_CAEEL (3-455): 0: 605: 63.60		HCP3_CAEEL (11-131): 7.65e-45: 149: 46.77
+	Mm
		952773 Q9JM08_MOUSE (9-434): 0: 568: 57.71		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Sc
		693050 RPD3_YEAST (8-421): 0: 580: 61.48		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Sp
		140575 PHD1_SCHPO (7-415): 0: 524: 52.91		H31_SCHPO (1-136): 4.67e-59: 180: 88.97
+	Sc
		859059 HOS2_YEAST (10-411): 2.72e-171: 491: 50.00		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Hs
		935199 HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086303 HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Sc
		866875 HDA1_YEAST (10-329): 4.19e-119: 366: 26.74		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Hs
		935331 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		H31_HUMAN (1-136): 6.88e-62: 187: 97.06