HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1250
+	Hs
		1031698 HDAC2_HUMAN (1-478): 0: 666: 85.92		GRB10_HUMAN (111-591): 4.23e-121: 389: 24.95
+	Hs
		1054075 HDAC2_HUMAN (1-478): 0: 666: 85.92		GRB7_HUMAN (217-590): 2.91e-120: 385: 23.61
+	Hs
		257609 HDAC1_HUMAN (1-482): 0: 668: 100.00		ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82
+	Hs
		257678 HDAC2_HUMAN (1-478): 0: 666: 85.92		ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82
+	Hs
		110768 HDAC1_HUMAN (1-482): 0: 668: 100.00		H7BXF5_HUMAN (515-1194): 3.96e-09: 63.3: 10.74
+	Dm
		1196991 HDAC1_DROME (6-477): 0: 658: 77.33		Q86BH2_DROME (642-1214): 2.13e-09: 64.5: 11.17
+	Hs
		177326 HDAC3_HUMAN (9-434): 0: 574: 57.94		ANR11_HUMAN (629-1247): 4.44e-09: 63.3: 10.58
+	Hs
		1056969 HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11		MDC1_HUMAN (718-1249): 2.96e-14: 80.3: 14.37