HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TF2LX (Q8IUE1)
Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X)
Gene: TGIF2LX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 241
+	Hs
		1216204 HDAC2_HUMAN (1-478): 0: 666: 85.92		TF2LX_HUMAN (1-241): 5.52e-55: 178: 100.00
+	Hs
		1038693 HDAC1_HUMAN (1-482): 0: 668: 100.00		TGIF2_HUMAN (33-240): 3.01e-42: 145: 40.72
+	Hs
		1038406 HDAC1_HUMAN (1-482): 0: 668: 100.00		TGIF1_HUMAN (26-236): 6.43e-37: 135: 32.05