HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1312
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (556-1225): 9.34e-25: 114: 11.92
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (524-1249): 1.05e-24: 114: 10.81
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (785-1235): 3.81e-15: 83.3: 13.32
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (785-1235): 1.33e-14: 81.7: 12.88
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (41-622): 1.09e-14: 81.7: 9.42
+	Hs
		148775 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		149134 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		1272047 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00
+	Hs
		177316 HDAC3_HUMAN (9-434): 0: 574: 57.94		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		1057383 HDAC8_HUMAN (32-371): 2.54e-139: 407: 43.11		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (52-818): 4.1e-25: 116: 8.56
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		1268107 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (46-651): 5.68e-16: 86: 8.67
+	Hs
		551864 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71