HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: ZN521 (Q96K83)
Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3)
Gene: ZNF521

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	31558698, 28514442, 33961781, 23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1311
+	Hs
		1270378 HDAC2_HUMAN (1-478): 0: 666: 85.92		ZN521_HUMAN (1-1311): 0: 730: 100.00
+	Mm
		1154009 Q9JM08_MOUSE (9-434): 0: 568: 57.71		ZN521_MOUSE (1-1311): 0: 725: 97.48
+	Hs
		1038427 HDAC1_HUMAN (1-482): 0: 668: 100.00		ZN423_HUMAN (5-269): 5.98e-12: 72.5: 15.19
+	Hs
		1101476 HDAC2_HUMAN (1-478): 0: 666: 85.92		ZN423_HUMAN (5-269): 5.98e-12: 72.5: 15.19