HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	20826751, 29378950, 12821938
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 391
+	Hs
		1270439 HDAC2_HUMAN (1-478): 0: 666: 85.92		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Hs
		1252805 HDAC2_HUMAN (1-478): 0: 666: 85.92		ARRD2_HUMAN (2-383): 5.07e-124: 365: 37.85
+	Hs
		177380 HDAC3_HUMAN (9-434): 0: 574: 57.94		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Hs
		685939 HDAC1_HUMAN (1-482): 0: 668: 100.00		ARRB2_HUMAN (15-323): 2.03e-60: 202: 12.18
+	Hs
		686023 HDAC2_HUMAN (1-478): 0: 666: 85.92		ARRB2_HUMAN (15-323): 2.03e-60: 202: 12.18