HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SMBT1 (Q9UHJ3)
Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1)
Gene: SFMBT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.699

The method score is based on:

Property Details
Experiments 27705803, 28514442, 33961781, 34709266
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 482
Hs

1 866
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Last updated: 15 Jul 2024