HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: BAZ2A (Q9UIF9)
Bromodomain adjacent to zinc finger domain protein 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3)
Gene: BAZ2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	26496610, 16085498
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Hist_deacetyl~MBD
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1905
+	Hs
		1038371 HDAC1_HUMAN (1-482): 0: 668: 100.00		DCTN1_HUMAN (392-1518): 5.64e-41: 168: 10.18
+	Hs
		998668 HDAC1_HUMAN (1-482): 0: 668: 100.00		EP300_HUMAN (1150-1900): 7.93e-41: 168: 12.63
+	Hs
		998937 HDAC2_HUMAN (1-478): 0: 666: 85.92		EP300_HUMAN (1150-1900): 7.93e-41: 168: 12.63
+	Hs
		170356 HDAC1_HUMAN (1-482): 0: 668: 100.00		TIF1A_HUMAN (1019-1902): 7.57e-40: 164: 14.74
+	Hs
		1018465 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD3_HUMAN (1541-1904): 7.58e-39: 162: 13.67
+	Hs
		170436 HDAC2_HUMAN (1-478): 0: 666: 85.92		TIF1A_HUMAN (1019-1902): 7.57e-40: 164: 14.74
+	Hs
		1018617 HDAC2_HUMAN (1-478): 0: 666: 85.92		CHD3_HUMAN (1541-1904): 7.58e-39: 162: 13.67
+	Hs
		177347 HDAC3_HUMAN (9-434): 0: 574: 57.94		KAT2B_HUMAN (1772-1896): 2.08e-44: 177: 37.30
+	Hs
		177279 HDAC3_HUMAN (9-434): 0: 574: 57.94		EP300_HUMAN (1150-1900): 7.93e-41: 168: 12.63
+	Sc
		693060 RPD3_YEAST (8-421): 0: 580: 61.48		GCN5_YEAST (1767-1898): 1.4e-39: 156: 33.33
+	Hs
		1017292 HDAC1_HUMAN (1-482): 0: 668: 100.00		BPTF_HUMAN (1676-1766): 1.74e-09: 65.7: 28.57
+	Hs
		1017332 HDAC2_HUMAN (1-478): 0: 666: 85.92		BPTF_HUMAN (1676-1766): 1.74e-09: 65.7: 28.57
+	Hs
		1038592 HDAC1_HUMAN (1-482): 0: 668: 100.00		CBP_HUMAN (86-477): 8.54e-09: 63.4: 9.52
+	Hs
		1270347 HDAC2_HUMAN (1-478): 0: 666: 85.92		CBP_HUMAN (86-477): 8.54e-09: 63.4: 9.52
+	Hs
		177346 HDAC3_HUMAN (9-434): 0: 574: 57.94		CBP_HUMAN (86-477): 8.54e-09: 63.4: 9.52
+	Hs
		998913 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		EP300_HUMAN (1150-1900): 7.93e-41: 168: 12.63
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (524-1597): 1.09e-47: 190: 11.74
+	Mm
		101450 HDA10_MOUSE (11-393): 4.64e-139: 416: 22.81		F8VPR5_MOUSE (86-449): 3.25e-09: 64.5: 11.08
+	Hs
		1051497 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DCTN1_HUMAN (392-1518): 5.64e-41: 168: 10.18
+	Hs
		999167 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		EP300_HUMAN (1150-1900): 7.93e-41: 168: 12.63