Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1
Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12032298, 11171972, 18806873, 34709266, 12192000, 15897453, 11102443, 26496610, 28514442, 33961781, 35271311, 33283408, 11602581, 17938259, 21258344, 23752268, 17939992, 17956988 |
| Identification Methods | biochemical, affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | association, physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding |
| Common GO terms | GO:0000118 - histone deacetylase complex GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
