HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 16611996, 10487760, 10655483
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 482
Hs

1 1011
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Rn
+ Mm
+ Hs
+ Hs
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+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024