HitPredict

Interactor 1: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 12482967, 20668654
Identification Methods enzymatic study, x-ray crystallography, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~CaMKII_AD, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004683 - calmodulin-dependent protein kinase activity
GO:0004723 - calcium-dependent protein serine/threonine phosphatase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 558
Hs

1 558
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+ Mm
+ Rn
+ Dm
+ Hs
+ Hs
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+ Dm
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Last updated: 15 Jul 2024