Interactor 1: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Interactor 2: KCC2A (Q9UQM7)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: CAMK2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 33961781, 32707033, 25852190, 32296183, 31980649, unassigned1304, unassigned2173
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~CaMKII_AD, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 558
Hs

1 478
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ At
+ Gm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024