Interactor 1: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Interactor 2: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 25416956, 18082144, 36949045, 20668654, 31515488
Identification Methods two hybrid, enzymatic study, two hybrid array, x-ray crystallography, cosedimentation in solution
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~CaMKII_AD, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0001558 - regulation of cell growth
GO:0002026 - regulation of the force of heart contraction
GO:0003254 - regulation of membrane depolarization
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
and 42 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 499
Hs

1 499
+ Hs
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+ Dm
+ At
+ At
+ Gm
+ At
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+ Dm
+ Mm
+ Rn
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Last updated: 15 Jul 2024