HitPredict

Interactor 1: DCTN2 (Q13561)
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)
Gene: DCTN2

Interactor 2: BICD2 (Q8TD16)
Protein bicaudal D homolog 2 (Bic-D 2)
Gene: BICD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	11483508, 34079125, 22956769
Identification Methods	two hybrid, pull down, proximity labelling technology, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 401 Hs			1 824
+	Mm
		1207171 DCTN2_MOUSE (1-401): 0: 536: 95.52		BICD1_MOUSE (11-813): 3.15e-54: 203: 60.98
+	Hs
		1039283 DCTN2_HUMAN (1-401): 0: 525: 100.00		BICD1_HUMAN (11-813): 1.24e-54: 206: 61.22
+	Dm
		561337 DCTN2_DROME (1-399): 2.13e-141: 409: 32.26		BICD_DROME (15-823): 6.26e-71: 250: 37.82
+	Hs
		1039272 DCTN2_HUMAN (1-401): 0: 525: 100.00		MY18A_HUMAN (6-719): 7.73e-11: 68.4: 17.85