HitPredict

Interactor 1: DCTN2 (Q13561)
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)
Gene: DCTN2

Interactor 2: ARP10 (Q9NZ32)
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Gene: ACTR10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	27173435, 26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Dynamitin
Common GO terms	GO:0005829 - cytosol GO:0005869 - dynactin complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 401 Hs			1 417
+	Hs
		891746 DCTN2_HUMAN (1-401): 0: 525: 100.00		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		929854 DCTN2_HUMAN (1-401): 0: 525: 100.00		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		932142 DCTN2_HUMAN (1-401): 0: 525: 100.00		ACTC_HUMAN (7-384): 4e-172: 487: 24.51
+	Dm
		1179205 DCTN2_DROME (1-399): 2.13e-141: 409: 32.26		Q9VWE8_DROME (1-394): 1.1e-92: 285: 40.25