Interactor 1: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2

Interactor 2: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 9192675, 19556541, 21622852, 27991905, 28092368, 27768895, 20168298
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, static light scattering, molecular sieving, comigration in non denaturing gel electrophoresis, cross-linking study, dynamic light scattering, x ray scattering, 3D electron microscopy and 3 others

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Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fer4_24~Fer4_24, PKD_channel~PKD_channel, PKD_channel~Polycystin_dom, Polycystin_dom~Polycystin_dom
Common GO terms GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0001889 - liver development
GO:0001892 - embryonic placenta development
GO:0001947 - heart looping
GO:0002133 - polycystin complex
and 97 others

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Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 968
Hs

1 968
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Last updated: 15 Jul 2024