Interactor 1: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2

Interactor 2: TPTE2 (Q6XPS3)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)
Gene: TPTE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.90 0.770

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~PKD_channel
Common GO terms GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008285 - negative regulation of cell population proliferation
Homologous interactions 0

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Last updated: 15 Jul 2024