Interactor 1: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2

Interactor 2: PK2L2 (Q9NZM6)
Polycystin-2-like protein 2 (Polycystin-2L2) (Polycystic kidney disease 2-like 2 protein) (Polycystin-L2)
Gene: PKD2L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PKD_channel~PKD_channel, PKD_channel~Polycystin_dom, Polycystin_dom~Polycystin_dom
Common GO terms GO:0005509 - calcium ion binding
GO:0016020 - membrane
GO:0050982 - detection of mechanical stimulus
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 968
Hs

1 624
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Last updated: 15 Jul 2024