HitPredict

Interactor 1: IRF5 (Q13568)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Interactor 2: IRF5 (Q13568)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 19786094, 18836453, 15556946, 16751392, 19430534, 12138184
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, molecular sieving, cosedimentation in solution
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF, IRF-3~IRF-3
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002376 - immune system process
and 21 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 498
Hs

1 498
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024