Interactor 1: IRF5 (Q13568)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 15695821
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0032481 - positive regulation of type I interferon production
GO:0032727 - positive regulation of interferon-alpha production
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 498
Hs

1 729
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Last updated: 15 Jul 2024