HitPredict

Interactor 1: G5EBF5 (G5EBF5)
DRBM domain-containing protein (RNA interference promoting factor)
Gene: rde-4

Interactor 2: DCR1 (P34529)
Endoribonuclease dcr-1 (EC 3.1.26.-) [Cleaved into: Death-promoting deoxyribonuclease (tDCR-1) (EC 3.1.21.-)]
Gene: dcr-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	23933256, 22179787, 16439208, 12110183
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm, Ribonuclease_3~dsrm
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016442 - RISC complex GO:0030422 - siRNA processing
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 385 Ce			1 1910
+	Ce
		103951 G5EBF5_CAEEL (1-385): 0: 801: 100.00		G5EDI8_CAEEL (2-582): 3.16e-81: 293: 21.80