Interactor 1: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1
Interactor 2: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 0.60 | 0.594 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19934264 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003713 - transcription coactivator activity GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 5 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
