HitPredict

Interactor 1: G5EBH3 (G5EBH3)
Spectrin beta chain
Gene: sma-1

Interactor 2: G5EC72 (G5EC72)
PDZ and LIM domain protein Zasp
Gene: alp-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030036 - actin cytoskeleton organization GO:0032432 - actin filament bundle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3953 Ce			1 425
+	Hs
		117245 ACTN1_HUMAN (53-532): 8.43e-111: 379: 42.74		PDLI1_HUMAN (11-293): 7.76e-75: 238: 23.95
+	Hs
		117257 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		PDLI1_HUMAN (11-293): 7.76e-75: 238: 23.95
+	Hs
		117270 ACTN3_HUMAN (53-542): 4.59e-108: 371: 42.07		PDLI1_HUMAN (11-293): 7.76e-75: 238: 23.95
+	Hs
		117234 ACTN4_HUMAN (53-585): 1.96e-107: 370: 40.41		PDLI1_HUMAN (11-293): 7.76e-75: 238: 23.95
+	Hs
		521502 ACTN1_HUMAN (53-532): 8.43e-111: 379: 42.74		PDLI4_HUMAN (9-298): 7.54e-62: 204: 19.29
+	Hs
		725662 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		PDLI3_HUMAN (11-294): 4.96e-61: 204: 17.07
+	Rn
		1149817 ACTN1_RAT (53-532): 7.05e-111: 379: 42.74		PDLI2_RAT (13-275): 7.44e-48: 168: 16.07
+	Rn
		1149816 ACTN4_RAT (53-585): 1.68e-107: 370: 40.41		PDLI2_RAT (13-275): 7.44e-48: 168: 16.07
+	Ce
		103419 G4S034_CAEEL (1181-3500): 4.43e-120: 430: 20.34		G5EFG1_CAEEL (96-288): 1.23e-12: 71.5: 15.82
+	Hs
		521616 ACTN1_HUMAN (53-532): 8.43e-111: 379: 42.74		SYP2L_HUMAN (7-218): 1.81e-27: 117: 15.32
+	Hs
		725700 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		SYP2L_HUMAN (7-218): 1.81e-27: 117: 15.32
+	Hs
		993296 ACTN3_HUMAN (53-542): 4.59e-108: 371: 42.07		SYP2L_HUMAN (7-218): 1.81e-27: 117: 15.32
+	Hs
		725714 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		SYNP2_HUMAN (13-215): 1.49e-20: 96.5: 16.44
+	Hs
		254383 ACTN1_HUMAN (53-532): 8.43e-111: 379: 42.74		LDB3_HUMAN (88-273): 1.5e-18: 89.9: 14.09
+	Mm
		1337461 ACTN2_MOUSE (53-588): 8.39e-108: 370: 40.19		LDB3_MOUSE (88-273): 6.9e-20: 94.2: 13.64
+	Hs
		254385 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		LDB3_HUMAN (88-273): 1.5e-18: 89.9: 14.09
+	Hs
		521623 ACTN1_HUMAN (53-532): 8.43e-111: 379: 42.74		PDLI7_HUMAN (50-284): 1e-14: 77.7: 13.12
+	Hs
		725704 ACTN2_HUMAN (53-833): 7.53e-109: 374: 32.83		PDLI7_HUMAN (50-284): 1e-14: 77.7: 13.12
+	Hs
		211672 ACTN4_HUMAN (53-585): 1.96e-107: 370: 40.41		PDLI7_HUMAN (50-284): 1e-14: 77.7: 13.12
+	Mm
		1186636 ACTN1_MOUSE (53-532): 8.43e-111: 379: 42.74		PDLI5_MOUSE (50-288): 2.65e-11: 67.3: 13.08